Your bloodwork decides this, not a questionnaire.
Xilo measures your hormone levels, puts a licensed provider on the result, and offers treatment only when that provider judges it clinically appropriate. If your numbers do not support treatment, we will tell you that instead of selling you something.
Prescription products require an online consultation with a licensed provider who determines whether a prescription is appropriate. A prescription is not guaranteed. Availability varies by state. Important safety information.
Total testosterone
Adult male referenceMost laboratories flag a total testosterone below roughly 300 ng/dL as low, but reference ranges differ between laboratories and assays, and a single value is not a diagnosis. Free testosterone, SHBG, your symptoms, your age, and the time of day the sample was drawn all change how a number should be read.
Low testosterone rarely announces itself
It arrives as a pattern rather than an event. These are the changes men most often describe before their first panel comes back.
Energy that does not recover
Flat by mid-afternoon regardless of sleep, and a sense that rest stopped restoring anything.
Reduced sex drive
Less interest, and a change in performance that feels like a dial was turned down rather than switched off.
Slower returns from training
Strength plateaus, recovery stretches out, and muscle becomes harder to hold than it used to be.
Mood and concentration
Shorter patience, more difficulty focusing, and a baseline mood sitting lower than it should.
Every one of these has other explanations
Sleep apnea, thyroid disease, depression, medication side effects, alcohol, and plain overwork all produce this same pattern. That is precisely why Xilo will not prescribe from a symptom checklist. Your labs and a licensed provider decide, and sometimes the answer is that the problem is somewhere else entirely.
What we measure before anyone prescribes
The baseline panel exists to answer two questions: are your levels actually low, and is something else causing the symptoms. Both matter, and the second is the one a symptom quiz cannot reach.
Baseline hormone panel
Drawn before any prescription| Marker | What it establishes |
|---|---|
| Total testosterone | The headline value, drawn in the morning when levels peak |
| Free testosterone | The fraction actually available to tissue, which total alone can hide |
| SHBG | The binding protein that explains a normal total with low free |
| Estradiol | Context for symptoms and a safety marker during treatment |
| LH and FSH | The upstream pituitary signals that locate where a problem starts |
| Prolactin | Screens for a pituitary cause that changes the whole plan |
| Thyroid panel | Rules in or out the most common mimic of low testosterone |
| Metabolic and blood count | Baseline safety values, including hematocrit, before any therapy |
Where the sample is drawn
Collection is through a CLIA-certified laboratory. Results are returned to you and to the reviewing provider, and you keep them whether or not you go on to treatment.
Follow-up is part of treatment
If you start therapy, levels and safety markers are rechecked so that dosing responds to measurement rather than to how a week happened to feel. Treatment without follow-up testing is not something we offer.
What would rule you out
Most sites in this category publish only the reasons to say yes. These are the findings and histories that make a provider decline, and they are worth knowing before you spend anything.
Levels in range
If your panel returns normal values and your symptoms have another likely cause, treatment is not appropriate, and the right outcome is a referral rather than a prescription.
Prostate or breast cancer history
An active or suspected hormone-sensitive cancer is a contraindication to testosterone therapy and requires management by your treating specialist.
Elevated hematocrit
Testosterone therapy raises red cell mass. A hematocrit already above the safe threshold has to come down and be investigated before therapy is considered.
Untreated sleep apnea, unstable cardiac or liver disease
Each changes the risk calculation enough that treatment waits until the underlying condition is being managed.
Actively trying to conceive
Some hormone therapies suppress sperm production. Tell your provider if fertility is a current goal, because it changes what can be offered and sometimes rules treatment out.
Under 18, or outside a state we serve
Xilo serves adults only. Availability varies by state and some states require a video visit. The eligibility check confirms your state before you pay anything.
Treatment options, compared honestly
Xilo offers oral therapies that support your body's own production. We do not offer injectable testosterone replacement through this platform, and the table says so rather than leaving it out.
Approach comparison
Mechanism and requirements| Approach | Form | Mechanism | Effect on fertility | Offered by Xilo |
|---|---|---|---|---|
| Production-support therapy | Once-daily oral | Acts on the pituitary signalling that drives your own testosterone production | Designed to preserve natural production | Yes, Rx |
| Production support with performance support | Once-daily oral, two part | The above, with a separate medication for erectile function | Designed to preserve natural production | Yes, Rx |
| Nutritional foundation | Daily capsule | Supplies cofactors that hormone production depends on. It is not a treatment for low testosterone | None expected | Yes, non-Rx |
| Injectable testosterone replacement | Injection | Replaces testosterone from outside the body, suppressing the body's own signalling | Can suppress sperm production and fertility | No |
The comparison describes general differences in mechanism between these categories of therapy. It is not a statement about how any individual will respond. The specific medication, if any, is selected by your provider based on your panel, your history, and your goals. Compounded drug products, where used, are not approved by the FDA and are not evaluated by the FDA for safety, effectiveness, or quality.
How care actually proceeds
Four steps, in this order, every time. The order is the point: nothing is prescribed before there is a result to prescribe against.
Eligibility check
A short intake covering symptoms, history, medications, and your state. It routes you and flags anything that would rule treatment out. It is not a diagnosis and it does not produce a prescription.
Baseline panel
Bloodwork through a CLIA-certified laboratory, drawn in the morning. Results return to you and to the reviewing provider.
Provider review
An independent, licensed provider reviews your panel and history and decides whether treatment is appropriate. Some states require a video visit. The provider may decline, and may refer you elsewhere.
Treatment and follow-up testing
If a prescription is written, medication ships to you and follow-up bloodwork confirms both response and safety markers. Dosing changes follow the numbers.
Plans
One price covering provider care, laboratory work, and medication where it is prescribed. Xilo does not bill insurance.
Production support
Provider consultation, baseline panel, follow-up testing, and medication if your provider prescribes it.
Check eligibilityProduction and performance
The production-support plan with an additional medication for erectile function, where clinically appropriate.
Check eligibilityNutritional foundation
Daily capsule supplying cofactors of hormone production. A starting point, and not a treatment for low testosterone.
Start hereAll prices are in US dollars. Plans bill monthly on the same date and renew until cancelled, and you can cancel any time before the next billing date from your account or by email. See refunds and cancellation and shipping and delivery. Prices do not include a prescription: whether one is written is a clinical decision made by your provider after review. If treatment is declined, you are not charged for medication. FSA and HSA eligibility varies by administrator.
Risks worth reading before you start
Hormone therapy carries real risk. This is a summary and not a substitute for the full safety information or for the conversation with your provider.
More commonly reported
Headache, nausea, acne, changes in mood, and changes in sleep. Report anything persistent to your provider rather than adjusting on your own.
Less common and serious
Visual disturbance, blood clots, a rise in hematocrit requiring dose change or discontinuation, and effects on fertility. Seek urgent care for chest pain, shortness of breath, leg swelling, or sudden vision change.
Mental health
If low mood is part of why you are here, tell your provider. If you are in crisis or thinking about harming yourself, call or text 988 in the United States to reach the Suicide and Crisis Lifeline, or call 911.
Questions men actually ask
What number counts as low?
Most laboratories flag total testosterone below roughly 300 ng/dL, but ranges differ by laboratory and assay, and one value is not a diagnosis. Free testosterone, SHBG, your symptoms, your age, and the draw time all change the reading. Your provider interprets the whole panel.
Will this affect my fertility?
The oral approaches Xilo offers are chosen to work through your own production pathway rather than replacing testosterone from outside, which is the mechanism most associated with suppressed sperm production. That is a difference in mechanism, not a guarantee about you. If you are trying to conceive now or expect to, say so during intake, because it directly changes what a provider can offer and may rule treatment out.
How quickly does anything change?
Laboratory values generally move before subjective changes do, which is exactly why follow-up testing is scheduled rather than optional. We do not publish a timeline for how you will feel, because the honest answer varies widely and the number on your follow-up panel is the thing we can actually show you.
What if the provider says no?
Then no prescription is written. You keep your laboratory results, you are not charged for medication, and where the panel points at another cause the provider will tell you what to pursue with your own physician. This outcome is common enough that it is not an edge case.
Do you take insurance?
No. Plans are priced directly and cover provider care, laboratory work, and medication where prescribed. FSA and HSA eligibility depends on your administrator, so check with them before purchasing.
Is Xilo available in my state?
Availability varies by state and some states require a video visit with your provider. The eligibility check confirms your state at the start, before any payment.
Is this the same company selling research peptides?
Xilo also operates a research supply line that sells laboratory reference materials to verified institutions. It is a separate line with separate fulfilment, and nothing from it is ever dispensed to a patient or offered as treatment. If you arrived looking for that, it is at the research supply page.
Find out where your levels actually sit.
The eligibility check takes a couple of minutes, confirms your state, and flags anything that would rule treatment out before you spend anything.